Wario Head

Wario Head, known for the "Obey Wario, Destroy Mario" meme, appeared in Ssenmodnar 8 (150k special), where Waluigi watched his meme and started going crazy whilst hurting X.

Wario Head also originally appears in the Super Mario Land 2: 6 Golden Coins commercial. The original version of his meme can be found here, while the long one is found here.