In the video Sonic the Derphog: The Item Brick, Dr. Pootis appears from the nominal Question Block after Dr. Eggman threw it on the ground. The two then continue to fight each other. The two fight once again in a later video titled, "Sonic the Derphog: Showdown of the Idiots".
Pootis originated in Paper Mario: The Thousand Year Door as Lord Crump where he was Sir Grodus's (the main villain) right hand.
The phrase "Pootis" is from Team Fortress 2. By starting and stopping the quote "Put dispenser here" you will get a quick "Pootis" or "Put dis". Due to the Heavy's strong accent, it sounds more like "Poot", bringing at the end "Pootis".
