Mario would first encounter Saiko Bichitaru sweeping the floor. When she asked him to help her, he did so but only swept once before declaring himself done and falling asleep, much to her annoyance. After getting hit by her thrown broom, Mario took out the Poltergust 3000 but hit the wrong setting, causing several ghosts (including Shigeru Miyamoto) to be ejected out of the vacuum cleaner. As Saiko yelled at Mario to help her, he just left the room.
Bob is unable to clean the basement because he is scared of MIPS, who was in possession of a gun. Mario tricks Luigi into entering the basement and getting shot multiple times.
Meggy was mopping the floor, however, due to the past events, she was struggling to do so. After some encouragement from Mario, she decides to clean the whole room by using a splattershot loaded with water, but she then starts using orange ink, saying she has "to train" and make a mess out of the room she was in, accidentally shooting Mario in the process.
Mario later encounters Fishy Boopkins, who is having a hard time cleaning the windows because of his stubby arms. Fishy Boopkins fell off after SMG4 grabbed Mario for his chores.
SMG4 calls Mario for help by taking out the trash. Mario does help but he starts making a giant mess by missing the dumpster while throwing the bags, which results in the bags being flung everywhere. SMG4 told Mario to stop and SMG4 said to him he'd do it by himself.
Lastly, Tari is doing the dishwashing, but Mario refuses to do that chore. They decide to play a game. Tari is washing the dishes, while Mario dries them. Mario then tells Tari many times to speed things up. She washed dishes so fast that she set her arms on fire and had to go to the lake to extinguish the flames.
Eventually, Peach returns with her Japanese shopping goods to see the castle in an even bigger mess than it was before she left. Understandably upset with Mario for making things worse, she turns into a creepy form and chases after him.
Saiko: Sweeping the floor in the Bob-Omb Battlefield room.
Bob: Clean the castle basement.
Meggy: Tries to mop the floor on the 2nd floor of the castle.
Boopkins: Washing the windows outside of the castle.
SMG4: Taking out thousands of garbage bags filled with dead memes.
Tari: Washing the dishes.
Here are the events Mario got tangled up in. There were mistakes that Mario made in the castle and that caused trouble to his friends:
Luigi: Not helping Luigi when his head was being bitten by a Piranha Plant, and then having him get attacked by MIPS the armed rabbit inside the basement.
Saiko: Summoning the ghosts out from the Poltergust 3000 in the Bob-Omb Battlefield room.
Bob: Getting chased by MIPS the armed rabbit.
Meggy: Causing her to splatter the entire castle with orange juice.
Boopkins: Making him fall into the castle moat and throwing a bag of garbage at him causing him to be sent flying.
SMG4: Intentionally throwing thousands of garbage bags filled with dead memes randomly, causing SMG4 to further retrieve them all over the area and throw them all out by himself just because Mario didn't want to help.
Tari: Constantly screaming either "faster" or "more" at her causing her hands to be set on fire due to friction. Also due to being in such a panic (or possibly because the sink had bleach/soap in it), she has to run out to the lake to put out the fire, despite the sink containing water was right in front of her.
SMG4: Final Hours: This episode takes place after the previous episode. Meggy is shown struggling to adapt to her new human body. Desti is also mentioned in this blooper.
SMG4: Mario Saves Anime: Peach maintains her love of anime. She was shown to possess many Japanese-related items such as manga and anime DVDs.